1. Exact global alignment using A* with chaining seed heuristic and match pruning 

   Koerkamp R.G.; Ivanov P. (2024)

   Bioinformatics

   Motivation: Sequence alignment has been at the core of computational biology for half a century. Still, it is an open problem to design a practical algorithm for exact alignment of a pair of related sequences in linear-like time. Results: We solve exact global pairwise alignment with respect to edit distance by using the A* shortest path algorithm. In order to efficiently align long sequences with high divergence, we extend the recently ...

   Journal Article

2. Characterization of genomic variation and its association with complex traits and gene expression in cattle 

   Bhati, Meenu (2024)

   Cattle play a pivotal role in agriculture, providing vital resources such as milk and meat, and have a special cultural significance. Domestication and human mediated selection have led to the diversification of cattle breeds worldwide. In recent decades, genomic technologies, in particular whole genome sequencing, have revolutionised our understanding of the genetic diversity within cattle populations. However, many aspects of their ...

   Doctoral Thesis

3. Noise reduction in absorption imaging for quantum gases experiments 

   Montalti, Nicolò (2024)

   Student Paper

4. Cutaneous and immune effects of photochemical-based vaccination in mice 

   Kotkowska, Zuzanna K. (2024)

   Vaccination is the medical intervention with perhaps the strongest impact on human health. Conventional vaccines have successfully prevented infectious diseases for more than a century by inducing long-lasting immune responses. Research and development during the last decades have shown that also cancer can be treated by engaging the immune system. However, while the immune system efficiently recognizes foreign protein antigens on pathogens, ...

   Doctoral Thesis

5. Escarpment evolution drives the diversification of the Madagascar flora 

   Liu, Yi; Wang, Yanyan; Willett, Sean D.; et al. (2024)

   Science

   Madagascar exhibits high endemic biodiversity that has evolved with sustained and stable rates of speciation over the past several tens of millions of years. The topography of Madagascar is dominated by a mountainous continental rift escarpment, with the highest plant diversity and rarity found along the steep, eastern side of this geographic feature. Using a process-explicit model, we show that precipitation-driven erosion and landward ...

   Journal Article

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